piperazine citrate

structural formula

• numbering system
• physical property data
• toxicological data
• ecological data
• molecular structure data
• computing chemical data
• more
  • properties and stability
  • storage method
  • synthesis method
  • purpose

numbering system

cas number:144-29-6

mdl number:mfcd00038961

einecs number:205-622-8

rtecs number:tl3485000

brn number:none

pubchem number:24870338

physical property data

1. physical property data

1. characteristics: white crystalline powder or translucent crystalline particles.

2. solubility:easily soluble in water, very slightly soluble in methanol, insoluble in ethanol, ether, chloroform and benzene.

3. boiling point (ºc,normal pressure): 182-187 ºc (decomposition)

toxicological data

2. toxicological data:

1, acute toxicity: oral administration to rats ld50 : 11200 mg/kg;

small rat oral ld50: 8500 mg/kg;

small mouse abdominal cavity ld50: 3548 mg/kg;

small mouse intravenous ldlo: 100 mg/kg;

rabbit intravenous ldlo: 175 mg/kg.

ecological data

3. ecological data:

other harmful effect: this substance may be harmful to the environment, and special attention should be paid to water bodies.

molecular structure data

none

compute chemical data

4. calculated chemical data:

1. hydrogen bonding number of donors: 6

2. hydrogen bonding number of receptors: 9

3. rotatable number of chemical bonds: 5

4. topological molecules polar surface area (tpsa）：156

5. heavy atoms quantity: 19

6. surface charge ：0

7. complexity ：254

8. number of isotope atoms: 0

9. determine the number of atomic stereocenters:0

10. uncertain number of atomic stereocenters:0

11. determine the number of stereocenters of chemical bonds:0

12. uncertain number of chemical bond stereocenters:0

13. number of covalent bond units: 2

properties and stability

stable under normal temperature and pressure. span>

storage method

save in a dry and cool place.

synthesis method

dissolve piperazine hexahydrate in distilled water, add activated carbon in 50-60℃decolorize for half an hour and filter. add citrate to the filtrate and add citric acid to 88-90 -family: 宋体”>℃stir 1.5 hours. cool to 35℃, add ethanol, cool and crystallize, filter, and dry to obtain the finished product.

purpose

1.anthelmintics, used for pinworm and roundworm infections.

2. used as an anthelmintic

amily: 宋体; mso-bidi-font-family: 宋体”>℃stir 1.5 hours. cool to 35℃, add ethanol, cool and crystallize , filtered and dried to obtain the finished product.

purpose

1.anthelmintics, used for pinworm and roundworm infections.

2. used as an anthelmintic